Table 5.
Correlation coefficients of hypertension-associated polymorphism MAFs with latitude.
| Polymorphism | Population | Adjusted Spearman Rank Correlation Score | Adjusted r2 |
| CYP3A5 g.6980G>A | CEPH-HGDP | -0.621** | 0.319 |
| CEPH-HGDP + HapMap | -0.620** | 0.349 | |
| CEPH-HGDP + HapMap + AIP | -0.603** | 0.302 | |
| AGT g.802C>T | CEPH-HGDP | -0.718** | 0.409 |
| CEPH-HGDP + Others | -0.693** | 0.373 | |
| CEPH-HGDP + Others + AIP | -0.518** | 0.248 | |
| GNB3 g.825C>T | Others | -0.620** | 0.278 |
| Others + AIP | -0.300* | 0.101 | |
* significant at 0.05, ** significant at 0.01
CEPH-HGDP = Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Panel.
AIP = Asian Indian population.
Others = data from other populations that were not part of CEPH-HGDP or HapMap.
For sample sizes, please see Additional file 1, Tables S4, S5, S6, for CYP3A5 g.6980G>A, AGT g.802C>T, and GNB3 g.825C>T, respectively.