Table 1. Group by State by Valence interaction.

ROIs, Group by State by Valence interaction	L/R	Vol mm3	Talairach coord. x y z	Gr. by St. by val. Inter. F-value	Neu (Med. vs Rest), t-value	(Pos+Neg)/2-Neu, t-value	Main effect verbal report, F-value	Interaction verbal report by Group, F-value
Ant. Insula/Inf. Frontal gyrus	R	3822	38 20 12/39 24 11	4.6	X (p>0.4)	2.3 (E>N)	6.6 (G>P)	X
Insula/post-/precentral gyrus	L	5005	−40 −1 17/−60 −6 18	4.3	X (p>0.4)	2.2 (E>N)	5.3 (G>P)	X
Sup.temporal gyrus/Inf. Parietal lobule (SII)/ post-central gyrus/ Insula	R	4802	60 −29 14/52 −26 27/54 −22 32/49 −30 19	4.6	2.3 (Med.>Rest)	2.2 (E>N)	X	X
Precuneus/Sup. Parietal Lobule	L	4102	−20 −54 39/−19 −62 53	4.1	X (p>0.4)	2.2 (E>N)	6.2 (G>P)	X

Clusters extracted from the ROIs showing Group by State by Valence interaction (p<0. 05 corrected, repeated ANOVA). T-test comparing responses during meditation minus resting states for experts (E) vs. novices (N) during neutral sounds (Neu.) and during either positive and negative sounds minus neutral sounds ((Pos+Neg)/2-Neu) were run within in each of these ROIs (p<0.05). A 2^*2 repeated ANOVA with verbal report (poor (P) vs. good (G)) and groups (experts vs. novices) was run in these ROIs on the response to positive and negative sounds during meditation blocks (12 experts and 10 novices). X indicates non-significant (p>0.05).