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Histologic profiles of the exocrine tissues of NOD.Igμnull mice after chronic treatment with control or Sjögren’s syndrome IgG fractions. The sections of submandibular, lachrymal, and pancreas were stained by hematoxylin/eosin and observed by light microscopy (×400). Sjögren’s syndrome patients #12 and 31, one stimulating secretion and the other inhibiting secretion, were used in this evaluation.
