Fig. 1.

General model schematic showing afferent cell groups and target cell relationships. Place cell firing is determined by the location of a simulated animal moving within a maze. Afferent cell groups are found in the entorhinal cortex (EC), which provides perforant path (PP) inputs, CA3 peer pyramidal cells, which provide associational connection (AC) inputs, and dentate gyrus (DG) granule cells, which provide mossy fiber (MF) inputs. Interneurons are divided into four separate population subgroups: axo-axonic cells (AA), basket cells (BC), bistratified cells (BS), and cells with soma in the stratum oriens and axons in strata lacunosum-moleculare (OL-M)