. Author manuscript; available in PMC: 2008 Nov 1.

Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2007 Sep 6;293(5):G995–1003. doi: 10.1152/ajpgi.00537.2006.

Table 2.

Mass of mucosa and muscularis layers of jejunum and colon in wild-type and IRS-1-null mice

	Genotype	Wet Weight, mg/cm	Protein, mg/cm	DNA, mg/cm	Protein/DNA Ratio	Sucrase Activity, U/cm
A: Jejunum
Mucosa	IRS-1^+/+	36.0±2.00	4.68±0.39	0.13±0.01	38.80±4.89	0.25±0.02
	IRS-1^−/−	35.1±2.00	4.71±0.52	0.08±0.01^*	63.03±8.28^*	0.23±0.02
Muscularis	IRS-1^+/+	11.7±0.40	1.69±0.13	0.15±0.01	11.31±1.02
	IRS-1^−/−	7.6±0.30^*	0.88±0.05^*	0.07±0.01^*	14.08±1.27
B: Colon
Mucosa	IRS-1^+/+	40.2±2.30	6.58±0.53	0.34±0.03	20.41±1.70
	IRS-1^−/−	29.1±2.10^*	3.58±0.31^*	0.17±0.02^*	22.62±2.77
Muscularis	IRS-1^+/+	14.7±0.50	2.02±0.10	0.25±0.02	8.18±0.48
	IRS-1^−/−	9.6±0.50^*	1.16±0.10^*	0.12±0.01^*	9.87±0.96

Values are means ± SE (n = 9 littermate pairs). Sucrase activity is shown for only jejunum.

P < 0.05 for values in IRS-1^−/− vs. IRS-1^+/+ mice.