Table 1B.
Regions with main-effects responses to bladder filling, for subjects with urge incontinence (n=10, threshold P = 0.01* uncorrected, FDR = 0.17)
| coordinates | Z-value | |||
|---|---|---|---|---|
| x | y | z | ||
| Cluster 1: fronto-temporal lobes, RI, ACG+claustrum, P < 0.000 (corrected) | ||||
| R. Inferior frontal gyrus (BA9, 44) | 52, 50 | 6, 8 | 32, 14 | 3.37, 3.53 |
| R. frontal lobe (BA6, precentral gyrus) | 40, 40 | -6, -2 | 54, 34 | 3.79, 3.37 |
| R/L. Medial frontal gyrus (BA6) | 12, -18 | 0, -4 | 56, 58 | 3.32, 3.32 |
| R. Frontal lobe (BA8) | 6 | 18 | 50 | 3.72 |
| R. sup.temporal gyrus (BA22) | 54 | 8 | -2 | 2.70 |
| ACG (BA32) | -4 | 16 | 38 | 4.33 |
| R.insula (BA13) | 38, 40 | -4, 6 | 16, 2 | 3.81, 3.80 |
| Claustrum | 30 | 14 | 8 | 4.35 |
| Cluster 2: parietal lobe+ paracentral/postcentral lobule, P < 0.000 (corrected) | ||||
| R. Inferior parietal lobule (BA40) | 36 | -44 | 44 | 3.92 |
| R. parietal lobe (BA5) | 20 | -44 | 50 | 3.72 |
| R.frontal lobe (paracentral lobule, BA5) | 16 | -40 | 56 | 2.80 |
| R. parietal lobe/postcentral gyrus (BA40) | 62, 62 | -34, -28 | 24, 18 | 2.84, 2.71 |
| Cluster 3: cerebellum, P < 0.02 | ||||
| Cerebellum (anterior lobe, culmen) | 24, 34 | -42, -54 | -30, -26 | 3.37, 3.22 |
| Cerebellum (posterior lobe, declive) | 20, 4 | -64, -66 | -20, -12 | 3.00, 2.93 |
| Trends: posterior cortex, P < 0.002 uncorrected, individually | ||||
| R. Occipital lobe (cuneus, BA17) | 16 | -92 | 8 | 3.09 |
| R. Occipital lobe (lingual gyrus, BA17) | 10 | -86 | 0 | 3.39 |
*
significant clusters better separated at this threshold level than at P = 0.05