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. Author manuscript; available in PMC: 2008 Mar 16.
Published in final edited form as: Neuropharmacology. 2007 Jan 20;52(6):1336–1341. doi: 10.1016/j.neuropharm.2007.01.005

Fig. 3.

Fig. 3

Buprenorphine induced CPP in wild-type but not in MOP knockout mice. Mice lacking the MOP [MOP (−/−)] and their wild-type littermates [MOP (+/+)] were tested for baseline preference on day 1 (A). Mice then received alternate-day saline/buprenorphine conditioning sessions on days 2–9. Mice were then tested for post-conditioning preference on day 10 (B). (C) Illustrates the difference in the amount of time (seconds) that the mice spent in the conditioning chambers (DPCh – VPCh) on days 1 and 10. Broken horizontal line indicates no preference. Data are expressed as mean (±S.E.M.) of 5–10 mice per genotype. VPCh, NCh and DPCh stand for vehicle-paired, neutral and drug-paired chambers, respectively.