Table.
Demographic and clinical characteristics
| Variable | IPAH (n=5) |
APAH (n=16) |
Controls (n=6) |
p value |
|---|---|---|---|---|
| Age, years | 45 ± 19 | 41 ± 12 | 34 ± 5 | 0.20 |
| Female, n (%) | 4 (80%) | 15 (94%) | 4 (67%) | 0.24 |
| Race/Ethnicity, n (%) | 0.56 | |||
| White/Non-Hispanic | 4 (80%) | 8 (50%) | 6 (100%) | |
| White/Hispanic | 0 (0%) | 3 (19%) | 0 (0%) | |
| Black/Non-Hispanic | 0 (0%) | 3 (19%) | 0 (0%) | |
| Black/Hispanic | 0 (0%) | 1 (6%) | 0 (0%) | |
| Asian/Non-Hispanic | 1 (20%) | 1 (6%) | 0 (0%) | |
| Body mass index, kg/m2 | 30 ± 8 | 26 ± 6 | 25 ± 5 | 0.47 |
| NYHA class, n (%) | 0.15 | |||
| II | 0 (0%) | 4 (25%) | ||
| III | 4 (80%) | 12 (75%) | ||
| IV | 1 (20%) | 0 | ||
| Mean right atrial pressure, mm Hg | 8 ± 3 | 9 ± 6 | 0.53 | |
| Mean pulmonary artery pressure, mm Hg | 63 ± 12 | 58 ± 14 | 0.48 | |
| Pulmonary vascular resistance, dynes·sec·cm−5 |
1467 ± 832 | 1425 ± 753 | 0.90 | |
| Cardiac index, liters/min/m2 | 1.7 ± 0.3 | 2.0 ± 0.7 | 0.39 | |
| Oxygen consumption at peak exercise, ml/min/kg |
9.6 ± 0.6 | 11.0 ± 4.5 | 1.0 | |
| Six-minute walk distance, meters | 364 ± 146 | 341 ± 122 | 0.80 |
Data are presented as mean ± sd and frequency (percentage). NYHA: New York Heart Association.