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Pathway of tyrosine degradation. After the first step of transamination of tyrosine with α-ketoglutarate (α-KG) to form glutamate and the ketoacid of tyrosine, the ketoacid is decarboxylated releasing the carboxyl-C as CO2. From there a series of steps opens up the aromatic ring, eventually forming fumarate and acetoacetate as end products.
