Fig. 4.

Summary of the four hemoglobin-uptake processes. (A) The timing and relative contribution of each hemoglobin-uptake pathway. The thickness of each bar represents the relative total aggregate volume of each of the indicated structures. Each vertical bar sums to 100%. (B) Total volume of internal hemoglobin as a percentage of parasite volume, demonstrating the dramatic nature of the Big Gulp. (C) Characteristics of the four hemoglobin-uptake structures. All times are given as time after invasion. Elongation factor is defined as the skeletal length of each vacuole divided by its diameter. SHV formation did not depend on actin (−uptake), whereas SHV transport was actin-dependent (+transport). Data not determined was marked ND.