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. 2008 Jan 16;15(3):522–533. doi: 10.1128/CVI.00432-07

FIG. 5.

FIG. 5.

IFN-γ production against four selected peptides derived from ML2283, ML1989, ML1990, or ML2567 in PBMC derived from PB leprosy patients (n = 6); MB leprosy patients (n = 4); patients with leprosy Rx (n = 4); HHC (n = 14); healthy controls from the area of endemicity without (EC Mlep−) (n = 5) or with (EC Mlep+) (n = 7) in vitro T-cell responses to M. leprae extracts; Dutch healthy, PPD-negative control individuals (NEC) (n = 10); Dutch TB patients (n = 10); and Dutch BCG-vaccinated individuals (n = 11). For each test group, the number of IFN-γ responders versus the total number of individuals in the group is indicated below the x axis. Horizontal bars indicate median responses. Dotted line shows 100-pg/ml cutoff value defining a positive response.