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. 2008 Jan 23;15(3):460–467. doi: 10.1128/CVI.00431-07

FIG. 1.

FIG. 1.

Experimental design for vaccination and filovirus challenge. Cynomolgus macaques were divided into two groups of five per group, and each group was vaccinated on days 0 and 63 with CAdVax-Panfilo or a control CAdVax vector. Group 1 was challenged with 1,000 PFU of MARV Musoke on day 105, and group 2 was challenged with 1,000 PFU of ZEBOV on day 106. Group 1 was subsequently back-challenged with 1,000 PFU of SEBOV on day 177, and group 2 was back-challenged with 1,000 PFU of MARV Ci67 on day 175. Filled arrows, vaccination; open arrows, virus challenge.