TABLE 2.
Sensitivities and specificities of the ELISA test for TB diagnosis
| ELISA | OD cutoff | No. of patients positive/no. tested
|
Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|
| TB patientsa | Control groupsb | ||||
| MPT-51 (IgM) | 0.560 | 33/49 | 3/98 | 77.6 | 96.9 |
| MPT-51 (IgG) | 1.140 | 2/49 | 2/98 | 4.1 | 98.0 |
| GlcB (IgM) | 0.730 | 4/49 | 4/98 | 8.2 | 95.9 |
| GlcB (IgG) | 0.876 | 9/49 | 1/98 | 75.5 | 65 |
| MPT-51 (IgM) + GlcB (IgG) | —c | 37/49 | 4/98 | 75.5 | 95.9 |
| MPT-51 (IgM + IgG) + GlcB (IgM + IgG) | — | 38/49 | 9/98 | 77.5 | 90.8 |
a
TB patient diagnosis based on M. tuberculosis culture and smear positivity.
b
Controls groups include healthy individuals and leprosy patients.
c
—, combined cutoff.