Figure 1.

Leukocyte rolling flux fractions (percent of all leukocytes rolling) in cremaster venules of adhesion molecule-deficient mice after treatment with TNF-α. Mice were pretreated with an intrascrotal injection of TNF-α 2.5 hr before the initiation of surgery. Values represent mean rolling flux fractions ± SEM from 14–47 venules. The data from wild-type and L-selectin^−/− mice are published (12). Differences between L-selectin^−/− and L-selectin/ICAM-1^−/− mice were significant (P < 0.05).