Table 1.

Numbers of blood leukocytes in L-selectin/ICAM-1-deficient mice

Cell lineage	No. of cells/ml (×10−5)
	Wild type	L-selectin−/−	ICAM-1−/−	L-selectin/ICAM-1−/−
Total	41  ± 5	51  ± 8	75  ± 7*	115  ± 8*†‡
Neutrophil	6.2  ± 1.1	8.6  ± 2.3	18  ± 3*	36  ± 4*†‡
Lymphocyte	34  ± 4	39  ± 7	50  ± 6*	68  ± 5*†‡
Monocyte	1.3  ± 0.3	3.2  ± 0.9*	4.2  ± 0.7*	8.3  ± 1.1*†‡
Eosinophil	0.9  ± 0.2	0.8  ± 0.5	2.5  ± 0.6*	3.0  ± 0.4*†

Differential leukocyte counts were performed on blood smear preparations following Wright–Giemsa staining. Values represent the mean ± SEM results from 13 wild-type, 9 L-selectin^−/−, 23 ICAM-1^−/−, and 37 L-selectin/ICAM-1^−/− mice. 

^*Differences between test and wild-type mice were significant, P < 0.05. 

^†Differences between L-selectin^−/− and L-selectin/ICAM-1^−/− mice were significant, P < 0.01. 

^‡Differences between ICAM-1^−/− and L-selectin/ICAM-1^−/− mice were significant, P < 0.05.