TABLE 4.
Gene expression changes in the presence of bile for genes chosen for disruption
| Gene | GenBank accession no. | Annotation | Change (fold) duringa:
|
|
|---|---|---|---|---|
| Bile shock | Bile adaptation | |||
| lr0004 | EF421856 | Clp chaperone (ClpE) | 5 | 1.4 |
| lr0085 | DQ233699 | Hypothetical protein | 3.3 | 2.5 |
| lr1265 | EU038268 | Multidrug resistance protein (ABC transporter family) | 3.9 | 1.5 |
| lr1291 | AY970991 | Metalloproteinase | 2.8 | 1.6 |
| lr1351 | DQ233687 | Conserved membrane protein of unknown function | 3 | 4.1 |
| lr1516 | DQ219970 | Putative esterase | 7.3 | 2.8 |
| lr1584 | EU038252 | Multidrug resistance protein (major facilitator superfamily) | 1.6 | 2.2 |
| lr1706 | EU038255 | Dps | 2.6 | 2.1 |
| lr1864 | DQ219976 | Clp chaperone (ClpL) | 3.2 | 1.4 |
a
Changes in boldface were found to be significantly different based on the outlier analysis.