TABLE 5.
In vitro activity of anidulafungin, caspofungin, and micafungin against bloodstream isolates of C. parapsilosisa
| Antifungal agent | No. tested | Cumulative % of isolates at an MIC (μg/ml) of:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0.015 | 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | ||
| Anidulafungin | 621 | 0.3 | 0.8 | 0.8 | 0.8 | 1.9 | 4.7 | 29.3 | 93.2 | 100 |
| Caspofungin | 1,447 | 0.3 | 0.9 | 3.7 | 12.4 | 49.9 | 89.4 | 98.8 | 99.6 | 100 |
| Micafungin | 539 | 0.2 | 0.2 | 0.2 | 0.6 | 5.2 | 22.5 | 75.3 | 100 | |
a
Isolates were tested in RPMI 1640 broth with 24 h of incubation and a prominent reduction endpoint criterion (MIC-2).