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Comparison of the phenotypes observed in the Trio-null embryos with netrin-1- and DCC-deficient embryos. Four different netrin-1- and DCC-dependent neuronal projections were examined in the Trio-null embryos, namely, the spinal commissural axon projections, the anterior commissure, the corpus callosum, and the internal capsule. The figure shows the comparison between the phenotypes observed in Trio-, netrin-1-, and DCC-deficient embryos (7, 13, 43).
