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Increased expression of mitochondrial and brown fat markers in BAT and WAT of LXRα−/− mice. RT-PCR analysis of genes in BAT (A) and WAT (C) of WT and LXRα−/− mice at 25°C. Data are expressed relative to those for the WT mice. Symbols: *, P < 0.05; **, P < 0.001; ***, P < 0.0001 versus corresponding gene in WT (two-tailed t test). Immunohistochemical staining for UCP1 in BAT (B) and gonadal WAT (D) from WT and LXRα−/− mice. All results are means ± SEM for five mice for each genotype.
