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BASE transmission in Tg(HuPrP) mice
| Inoculum | Attack rate as determined by:
|
Incubation time (days) | ||
|---|---|---|---|---|
| Clinical signs | Presence of PrPSc | Spongiform degeneration | ||
| BASE-1 | 4/15 | 9/15 | 1 (focal)/8 | 649 ± 34 |
| BASE-2 | 6/15 | 9/15 | 1 (focal)/11 | 595 ± 28 |
| sCJDMM1 | 10/10 | 9/10 | 4/4 | 263 ± 13a |
| sCJDMM2 | 9/9 | 9/9 | 7/7 | 267 ± 17 |
Reported previously (13).
