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Absence of IRF-3 activation establishes persistence
| Persistently infected cell line | Characterization | Passage no. | Viral titer (PFU/ml) |
|---|---|---|---|
| HT1080/siIRF-3/SeV | IRF-3 ablated | 21 | 2.4 × 103 |
| HT1080/RIG-Ic/SeV | Dominant-negative RIG-I | 20 | 2.1 × 105 |
| P2.1/SeV | Very low IRF-3 | 22 | 5.0 × 104 |
