Table 1.
CHO CM | 7PA2 CM | |
---|---|---|
% new spines | 3.2 ± 1.1 | 0.2 ± 0.2** |
% spine loss | 1.5 ± 0.5 | 30 ± 5.9** |
% filopodia outgrowth | 3.4 ± 0.7 | 34 ± 2.9*** |
filopodia half-life (min) | 4.7 ± 0.7 | 222 ± 30** |
p < 0.01, and
p < 0.001 indicate values significantly different using Student’s t-test. Percentages were calculated over a period of 10.8 ± 4.5 hrs (CHO CM) and 13 ± 4.3 hrs (7PA2 CM). no. of filopodia used to measure filopodia half life: CHO CM=12; 7PA2 CM= 79. no. of dendritic regions used to calculate percentages: CHO CM=8 (no. of cells 6); 7PA2 CM=10 (no. of cells=8).