Skip to main content
. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Mol Cell Neurosci. 2007 Feb 12;35(2):183–193. doi: 10.1016/j.mcn.2007.02.006

Table 1.

Aβ affects dendritic spine and filopodia turn-over

CHO CM 7PA2 CM

% new spines 3.2 ± 1.1 0.2 ± 0.2**
% spine loss 1.5 ± 0.5 30 ± 5.9**
% filopodia outgrowth 3.4 ± 0.7 34 ± 2.9***
filopodia half-life (min) 4.7 ± 0.7 222 ± 30**
**

p < 0.01, and

***

p < 0.001 indicate values significantly different using Student’s t-test. Percentages were calculated over a period of 10.8 ± 4.5 hrs (CHO CM) and 13 ± 4.3 hrs (7PA2 CM). no. of filopodia used to measure filopodia half life: CHO CM=12; 7PA2 CM= 79. no. of dendritic regions used to calculate percentages: CHO CM=8 (no. of cells 6); 7PA2 CM=10 (no. of cells=8).