Fig. 5.
Phospholipid metabolism in Lands' cycle. Fatty acids of phospholipid are liberated by PLA2s and converted to eicosanoids. Lysophospholipids are also precursors of a different class of lipid mediators including PAF, LPA, and endocannabinoids. Lysophospholipids are converted to phospholipids in the presence of acyl-CoA by LPLATs. X indicates several polar head groups of phospholipids. See text for details.