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PolIVa is required for siRNA accumulation at most endogenous loci. (A) Representative Venn diagram of siRNA-generating loci. Solid line, loci with siRNAs in WT; dotted line, loci with siRNAs at WT or a greater level in nrpd1a; dashed line, loci with siRNAs present at WT or greater level in nrpd1b. (B and C) Pie charts depicting level of siRNA representation at loci requiring at least one PolIV isoform (gray region in A).
