Figure 10. Intraperitoneal glucose and insulin tolerance tests with iPLA2β-null and wild-type mice.
In Panel A D-glucose (2 mg/g) and in Panel B human regular insulin (0.75 units/kg) was administered by intraperitoneal injection to wild-type (open circles) or iPLA2β-null (closed circlers) male mice 20-24 wk of age, and blood was collected at baseline and at 30, 60, and 120 min after injection to measure glucose concentration. Values are displayed as mean ± SEM (n = 20). An asterisk (*) denotes p < 0.05 for the comparison between wild-type and iPLA2β-null mice.