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. Author manuscript; available in PMC: 2008 Mar 17.
Published in final edited form as: Breast Cancer Res Treat. 2007 May 17;108(1):43–55. doi: 10.1007/s10549-007-9587-7

Fig. 9.

Fig. 9

Evaluation of liver toxicity of the single-level and dual-level controlled CRAd in a human liver tissue slice model. Viral copy number as an indicator of viral replication in precision cut tissue slices of normal human liver obtained from three individual donors. Growth medium was collected at day 2 and 4 after infection with Ad-CXCR4-E1A, Ad-CXCR4-UTR-E1A, Ad-CXCR4-GL3 (negative control) or Ad-wt-dE3 (positive control). Each bar represents the mean of three experiments ±SD. *P < 0.05 Ad-CXCR4-UTR-E1A versus Ad-CXCR4-E1A and Ad-wt-dE3.