Figure 2.

Total motor horizontal activity during 5 min of test in an open field arena (a) and total immobility time during 10 min of FST (b) in male and female rats administered intraperitoneally (i.p.) with control saline solution (n = 24) or LPS (2 mg/kg). The animals were tested after 12 h (n = 24) or 24 h (n = 24) after administration. Values are means±SEM. *Significant differences with respect to control saline conditions (*p<0.05; **p<0.01).