Table 1.
Characteristics of the 2,476 subjects by final diagnoses*
| dementia | prevalent N=266 | incident N=236 | no N=1,974 | P-value† |
|---|---|---|---|---|
| age (yr) | 81.8 (7.1) | 79.6 (6.5) | 75.8 (6.0) | <0.001 |
| sex (% female) | 75.9 | 67.4 | 65.9 | 0.005 |
| ethnic-group (%) Caucasian | 8.7 | 12.3 | 31.7 | |
| African- American | 33.3 | 30.2 | 31.1 | <0.001 |
| Hispanic | 58.0 | 57.4 | 37.2 | |
| education (yrs) | 6.1 (4.1) | 7.2 (4.1) | 10.4 (4.6) | <0.001 |
| APOE-ε4 (%) | 34.5 | 30.3 | 26.9 | 0.02 |
| smoking (% current/ever) | 18.1 | 31.4 | 10.2 | <0.001 |
| waist (cm) | 91 (12) | 90 (13) | 93 (12) | <0.001 |
| HDL cholesterol (mg/dL) | 47 (14) | 47 (14) | 48 (15) | 0.44 |
| triglycerides (mg/dL) | 156 (80) | 169 (84) | 161 (87) | 0.19 |
| syst BP (mmHg) | 135 (21) | 134 (21) | 141 (22) | <0.001 |
| diast BP (mmHg) | 91 (12) | 90 (13) | 93 (12) | <0.001 |
| diabetes (%) | 30.1 | 29.2 | 21.0 | <0.001 |
| hypertension (%) | 77.1 | 78.0 | 70.8 | 0.01 |
| hyperinsulinemia, highest quartile (%) | 25.5 | 29.7 | 22.9 | 0.09 |
| metabolic syndrome (%) | 52.3 | 54.7 | 54.1 | 0.83 |
SI conversion factors: to convert HDL cholesterol to mmol/L, multiply by 0.0259; triglycerides to mmol/L, multiply by 0.0113.
*
values are mean (SD) or %
†
based on analysis of variance for continuous data and on χ2-test for categorical data