Table 2.

Estimated yearly rates of ventricular expansion for subjects with AD and FTLD-U

Time from CDR-SB of 6	Time-specific slope in ml per year (95% confidence interval)
	Adjusted			Unadjusted
	AD	FTLD-U	p value*	AD	FTLD-U	p value*
2 years prior	3.6 (-1.1, 8.3)	3.9 (-1.4, 9.3)	0.924	4.2 (-0.9, 9.3)	5.4 (-0.1, 11.3)	0.749
1 year prior	4.0 (-0.4, 8.5)	5.6 ( 0.8, 10.4)	0.626	4.9 (0.2, 9.5)	7.2 (2.1, 12.2)	0.497
0 years	4.5 ( 0.2, 8.8)	7.2 ( 2.8, 11.7)	0.358	5.6 (1.1, 10.0)	9.0 (4.4, 13.5)	0.285
1 year post	4.9 ( 0.6, 9.3)	8.9 ( 4.5, 13.3)	0.186	6.3 (1.8, 10.7)	10.7 (6.3, 15.2)	0.157
2 years post	5.4 ( 0.9, 9.9)	10.6 ( 5.9, 15.2)	0.102	7.0 (2.3, 11.6)	12.5 (7.7, 17.3)	0.100
3 years post	5.8 ( 1.0, 10.6)	12.2 ( 7.0, 17.4)	0.066	7.7 (2.6, 12.7)	14.3 (8.8, 19.8)	0.078
4 years post	6.2 ( 1.0, 11.5)	13.9 ( 8.0, 19.7)	0.050	8.4 (2.8, 14.0)	16.1 (9.7, 22.5)	0.073

^*Tests the null hypothesis that the slopes are different between AD and FTLD-U at the time indicated

Models are shown with and without adjustment for age, gender, and education

AD = Alzheimer’s disease; FTLD-U = frontotemporal lobar degeneration; CDR-SB = Clinical Dementia Rating scale-sum of the boxes score