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Stimulatory effect of monosubstituted CII 261–273 alanine analogs on four different HLA-DRB1*0401 and CII 261–273 specific T cell hybridomas. Putative positions in the HLA-DRB1*0401 binding pocket (P-2 to P11) of the amino acids in the CII261–273 peptide are indicated.
