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. 1998 Jun 23;95(13):7574–7579. doi: 10.1073/pnas.95.13.7574

Figure 2.

Figure 2

Collagen-induced arthritis in DR4 and human CD4 transgenic/Abβ0/0 mice. Plantar (A) and dorsal (B) views of rear paws of a DR4 and human CD4 transgenic/Abβ0/0 mouse (right) and a transgene negative Abβ0/0 littermate (left). Peripheral joints of the transgenic mouse are severely affected showing erythema and swelling, which decreased after 3–4 weeks leaving the affected paws deformed.