Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Dec 7;13:2263–2274.

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Biodistribution of rhodamine-conjugated-liposomes in cervical LN in healthy rats 24 h following IVT injection of VIP-Rh-Lip. A: Following IVT injection, VIP-Rh-Lip (red) are located within subcapsular sinus macrophages stained with ED3 (green). OX6-positive cells in blue are located in close proximity (arrow) with ED3-positive macrophages containing VIP-Rh-Lip. B: T lymphocytes recognized by their TCR expression (green) are localized in contact (arrow) with subcapsular macrophages containing VIP-Rh-Lip (red). C: Subcapsular sinus macrophages (asterisk) containing VIP-Rh-Lip (red) express CD4 in green and are in contact with CD4-positive lymphocytes (arrow). D: CD8-positive T lymphocytes (green) are also adjacent with VIP-Rh-Lip (red)-bearing macrophages. In B, C, and D nuclei are stained in blue with Toto3®-iodide. All bars represent 5 μm. Confocal microscopy optical sections are 1.5 μm in all images. Representative images of four experiments performed on cervical LN from four rats.