Fig. 2.

T cell expression of MyD88 is required for resistance to the pathogen T. gondii independent of the innate response. (A) Mice were inoculated i.p. with T. gondii and monitored for survival. Data are pooled from two experiments (n = 13 each cohort). (B) PECs isolated from mice on day 7 after infection was used to prepare cytospin smears. Data are the mean of three pooled experiments (n = 6). (C) Sera obtained from mice on day 5 of infection were evaluated by ELISA. Data are representative of three experiments. (D) Cells were isolated from draining lymph nodes and spleen on day 8 of infection and analyzed by flow cytometry. Data are representative of two experiments (n = 6 total for each cohort).