Table 1.

Physiological characterization of body composition, glucose and insulin levels, and ultrastructural analysis of Syt7^−/− and control mice

Characteristic	Control mice		Syt7−/− mice		Statistics
	Mean ± SEM	No.	Mean ± SEM	No.
Body weight, g	30 ± 0.5	41	27 ± 0.5	44	P < 0.001
Body fat, %	11.3 ± 0.7	9	7.6 ± 0.6	13	P < 0.001
Body lean, %	74.9 ± 0.7	9	78.3 ± 0.6	13	NS
Fasting glucose, mmol/liter	6.2 ± 0.4	13	6.2 ± 0.3	17	NS
Resting glucose, mmol/liter	8.3 ± 0.4	17	8.4 ± 0.3	17	NS
Fasting insulin, ng/ml	0.27 ± 0.07	14	0.16 ± 0.03	16	P < 0.05
Resting insulin, ng/ml	1.02 ± 0.16	12	0.74 ± 0.14	15	NS
Islet area (×1,000 μm2)	16.6 ± 4.9	36	17.4 ± 2.8	26	NS
Cell number per 100 μm2 of islet area	55 ± 3	23	53 ± 2	25	NS

NS, not significant.