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. 2008 Feb 28;105(10):3825–3830. doi: 10.1073/pnas.0709717105

Fig. 1.

Fig. 1.

Characterization of conditional ligands for HLA-A1, -A3, -A11, and -B7. (A) Control and p*-HLA complexes for each complex were exposed to UV for the indicated times, and UV-induced MHC unfolding was measured by ELISA. Control peptides: pA1 VTEHDTLLY, pA2 FLWGPRALV, pA3 RLRAEAQVK, pA11 IVTDFSVIK, and pB7 RPHERNGFTVL. (B) The indicated p*-HLA complexes were exposed to UV light for 0 or 60 min in the presence of no peptide, the HLA-A2 restricted CMV-pp65 epitope NLVPMVATV (irrelevant peptide), or their respective specific ligands, pA1, pA3, pA11, and pB7 (sequences under A) and analyzed by MHC-ELISA. Values indicate means ± SD of triplicates.