Table 4. Association tests, odds ratios, and population attributable risk percent (PAR%) for three SNPs of the LOXL1 gene.
|
Genetic test |
rs1048661
(R141L) |
rs3825942
(G153D) |
rs2165241 |
||||||
|
p-Value |
Odds |
PAR % |
p-Value |
Odds |
PAR % |
p-Value |
Odds |
PAR % |
|
| Homozygote |
1.00x10-6 |
0.088 |
7 |
5.00x10-5 |
0.001 |
4 |
5.39X10-22 |
0.069 |
38 |
| Heterozygote |
3.4x10−5 |
0.488 |
14 |
2.46x10-12 |
0.195 |
15 |
1.11X10-11 |
0.275 |
34 |
| Dominant |
2.72x10-7 |
0.421 |
19 |
2.31x10-15 |
0.165 |
19 |
6.09x10-19 |
0.203 |
54 |
| Recessive |
2.89x10-5 |
0.116 |
4 |
7.02x10-5 |
0.001 |
3 |
1.38x10-13 |
0.149 |
15 |
| Alleles | 7.74x10-9 | 0.442 | 28 | 3.10x10-17 | 0.168 | 58 | 4.85x10-24 | 0.294 | 32 |
Note that p-values provided under each of these three SNPs were obtained by comparing only the rare genotypes or alleles against other genotypes or alleles, respectively.