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. Author manuscript; available in PMC: 2008 Apr 8.
Published in final edited form as: Blood. 2007 Mar 5;109(11):4914–4923. doi: 10.1182/blood-2006-08-043232

Figure 6. HPSE is expressed by BM environment cells and by a minor subpopulation of myeloma cells.

Figure 6

A. XG-2 and XG-7 cells were stained with control rabbit polyclonal antibodies (Ab) (panel a) or with a polyclonal anti-HPSE Ab at 4.5 μg/ml (panels b,c). Note the dot-like staining signal. B. BM biopsies from patients with MM were stained with the polyclonal anti-HPSE Ab (4.5 μg/ml). Panels d–f: environment cells in the BM of one patient representative of twenty. PMN, polymorphonuclear cells; Meg, megakaryocytes. Panels g–j: heterogeneous HPSE expression among MMC in the bone marrow of four representative patients (g=patient 1; h=patient 4; i=patient 11; j=patient 20; see Table 3). The brown reaction product indicates the location of polyclonal Ab against HPSE. Original magnification of 1000× (or200× in f).