Table 2. Clinical data for HPSE^high and HPSE^low patients.

Thirty newly-diagnosed patients with MM were separated in two subgroups (HPSE^high and HPSE^low) according to HPSE gene expression in the WBM, assayed with Affymetrix U133 microarrays. Data are the percentages of patients within each subgroup with the indicated clinical or biological parameters. Statistical comparisons were made with the Chi square test. Data are shown in italics when the percentages between the two groups are significantly different.

	HPSElow n=15	HPSEhigh n=15
	% of patients in each subgroup		P =
Age ≥ 65 years	13	27	0.36
Beta2-microglobulin < 3.5 mg/l > 5.5 mg/l	80 0	47 27	0.05 0.03
C-reactive protein > 5 mg/l	7	40	0.03
Lactate dehydrogenase ≥ 240 mmol/l	20	27	0.66
Albumin < 35 g/l	33	40	0.7
Hemoglobin < 10 g/dl	20	47	0.1
Ca++ < 2,65 mmol/l	100	100	1
Kappa light chain	67	53	0.45
Lambda light chain	33	47	0.45
IgA subtype	20	13	0.61
Bone lesions ≥ 3	15	23	0.61
t(4;14)	15	0	0.14
del(chr13)	62	46	0.39
DS classification			0.82
Stage I	13	7
Stage II	20	20
Stage III	67	73
ISS classification			0.008
Stage 1	47	7
Stage II	53	60
Stage III	0	33