Figure 3. RV calpastatin.
Western immunoblots of myocardium from six RVPO vs six SHAM pigs (Series 1) probed for calpastatin; *: p < 0.05 RVPO vs SHAM. There is a trend toward reduction of the 110 kDa calpastatin band by 20% (p=0.3), a significant reduction in the 41 kDa calpastatin band of 23% (p=0.04), and a significant increase in the low molecular weight band of 60% (p=0.02) resulting from RV pressure overload.