Skip to main content
. Author manuscript; available in PMC: 2009 Feb 15.
Published in final edited form as: Bioorg Med Chem. 2007 Nov 5;16(4):1903–1913. doi: 10.1016/j.bmc.2007.11.001

Figure 3.

Figure 3

Four clusters of epitopes recognized by selected Fabs. The picture depicts a set of potential epitopes (overlapping circles), as defined by the selected Fabs binding to the PA63 heptamer surface (PDB code: 1TZO). Fab A8 recognizes an epitope within LF/EF binding site. Fabs F1 and G12, F11 and G3, and G11, H2 and 83H2 all recognize a similar epitope near the PA cellular receptor binding site. The later three clusters also have epitopes overlapping with each other but with less homology than the other identified epitopes.