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Kinetic constants determined for all neutralizing Fabs by Biacore 3000.
| Fab | ka (1/Ms) | kd (1/s) | KA (1/M) | KD (M) |
|---|---|---|---|---|
| A8 | 3.47 × 104 | 3.78 × 10−3 | 9.17 × 106 | 1.09 × 10−7 |
| F1 | 2.71 × 104 | 1.38 × 10−3 | 1.96 × 107 | 5.09 × 10−8 |
| G11 | 2.84 × 104 | 2.31 × 10−3 | 1.23 × 107 | 8.13 × 10−8 |
| G12 | 4.03 × 104 | 1.96 × 10−2 | 2.13 × 106 | 4.68 × 10−7 |
