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Sensitivity of HIV-1 R5 envelopes to inhibition by Q4120 and PRO 542 correlates with macrophage-tropism. HIV-1 R5 macrophage-tropism correlated with an increased sensitivity to PRO 542 but decreased sensitivity to Q4120 and BMS378806. HIV-1 R5 macrophage-tropism also correlated with sensitivity to 2G12 but not with b12, TAK779, SCH350581 or T20 (see complete list of p values in Table 2).
