Table I.

Hematopoietic expansion potential of hematopoietic stem and progenitor cells (HSPCs) from P-selectin capture tubes and peripheral blood, given as the number of hemoglobinized erythroblasts and granulocyte/monocyte precursors were observed in both BFU and CFU colonies after 3–4 weeks.

Hematopoietic Colony Type	P-selectin Captured MNCs (105 cells)	Peripheral Blood MNCs (105 cells)	Peripheral Blood MNCs (106 cells)
CFU-GM (# colonies)	1.5 (2 of 5 plates active)	1.5 (2 of 7 plates active)	14.4 (5 of 6 plates active)
BFU-E (# colonies)	1.5 (2 of 5 plates active)	0.5 (2 of 7 plates active)	4.0 (5 of 6 plates active)

Viable blood-borne HSPCs from implanted P-selectin coated tubes and rat whole blood expand to similar numbers of colony-types in culture (counts are given as average number of colonies per active plate). The presence of erythroid and granulocyte/monocyte colonies indicates that implantable P-selectin tubes have the capacity not only for HSPC capture and enrichment, but also for short-term maintenance of viable progenitors with the potential for differentiation and proliferation.