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. Author manuscript; available in PMC: 2008 Mar 19.
Published in final edited form as: Antioxid Redox Signal. 2008 Feb;10(2):269–275. doi: 10.1089/ars.2007.1910

FIG. 2. Lung histology and fibrosis 14 days after intratracheal asbestos and bleomycin. Hematoxylin and Eosin (H&E) staining and Masson's trichrome staining were performed on lung sections 14 days after exposure.

FIG. 2

(A) Histological micrograph 14 days after intratracheal asbestos (0.1 mg) showed increased cellularity and lung inflammation characterizied by numerous inflammatory cells and erythrocytes within the alveolar spaces and interstitium, in a peribronchial distribution. (B) Masson's Trichrome staining after intratracheal asbestos showed interstitial collagen deposition (blue staining within the interstitium. (C) Micrograph of lung histology after intratracheal bleomycin (2 mg/kg) revealed lung inflammation. Note the numerous inflammatory cells and erythrocytes within the alveolar spaces and interstitium. Note presences of intraalveolar and interstitial inflammatory cells. (D) Masson's Trichrome staining after intratracheal asbestos showed diffuse collagen deposition (blue staining) in the interstitium. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article at www.liebertonline.com/ars).