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. 2008 Jan 3;586(Pt 4):1029–1042. doi: 10.1113/jphysiol.2007.145219

Figure 7. Ca2+ current inactivation during repetitive stimulation.

Figure 7

A, Ca2+ currents recorded from an immature (P7) basal IHC in response to a train of 50 ms voltage steps to −11 mV from a holding potential of −81 mV. Time between voltage steps was 100 ms (see protocol: top panel). Note that for clarity only 800 ms (total protocol duration: 3.5 s) is shown. B, Ca2+ currents recorded from an immature (black) and an adult (grey) basal IHC. Immature IHC: Cm 7.7 pF, Rs 5.0 MΩ, gleak 1.9 nS; Adult IHC: Cm 10.7 pF, Rs 4.8 MΩ, gleak 0.8 nS. C and D, average peak Ca2+ current normalized to that elicited by the initial depolarizing step, obtained using the protocol described in A from adult (apical: n = 6; basal: n = 4) and immature (apical: n = 3; basal: n = 5) IHCs.