Figure 7.

Inhibition of Th2 effector function in vivo. Th2-recipient mice were exposed to OVA aerosols. Twenty-four hours after the last aerosol challenge BAL was performed, and differential cell counts and cytokine ELISA were done. (A) Mice received either T1/ST2-specific mAb 3E10 (open bars) or rat IgG as isotype control (solid bars) 1 hr before OVA challenge. (B) Mice received either T1/ST2–IgG fusion protein (open bars) or human IgG (solid bars). Data are shown as the mean ± SEM of 4–6 animals.