Table 3.

Exchange of amino acids (μmol min⁻¹) in the normal-glycogen leg at rest, during exercise and repeatedly during the recovery period

			Recovery
Amino acid	Rest	Exercise	5 min	15 min	30–120 min	Recovery
Glutamate	13 ± 1*	39 ± 8*	15 ± 3	14 ± 2	14 ± 3	P < 0.05
Serine	1 ± 1	−21 ± 34	−7 ± 4	−10 ± 4	−5 ± 1	P < 0.05
Glutamine	−27 ± 5*	−97 ± 126	−58 ± 17	−62 ± 19	−36 ± 6	P < 0.05
Histidine	−3 ± 1*	−13 ± 18	−6 ± 3	−6 ± 3	−3 ± 0.5	P < 0.05
Glycine	−6 ± 1*	−44 ± 41	−15 ± 6	−20 ± 6	−12 ± 2	P < 0.05
Threonine	−4 ± 1*	−20 ± 26	−14 ± 4	−15 ± 4	−10 ± 2	P < 0.05
Alanine	−30 ± 4*	−195 ± 71*	−55 ± 11	−69 ± 22	−41 ± 9	P < 0.05
Taurine	−1 ± 0.3	−16 ± 12	−5 ± 2	−5 ± 2	−1 ± 0.6	n. s.
Arginine	−3 ± 1*	−24 ± 14	−5 ± 2	−9 ± 3	−4 ± 1	P < 0.05
Tyrosine	−2 ± 0.4*	−8 ± 14	−5 ± 2	−5 ± 2	−2 ± 0.5	P < 0.05
Methionine	−1 ± 0.2*	−8 ± 6	−3 ± 1	−3 ± 1	−2 ± 0.3	P < 0.05
Valine	0 ± 1	−47 ± 68	−6 ± 9	−14 ± 10	0 ± 3	n.s.
Tryptophan	0 ± 0.2	−12 ± 11	−1 ± 1	−3 ± 2	−1 ± 0.3	n. s.
Phenylalanine	−2 ± 0.3*	−15 ± 13	−4 ± 1	−6 ± 2	−2 ± 0.4	P < 0.05
Isoleucine	−1 ± 0.5	−12 ± 19	−1 ± 3	−4 ± 3	0 ± 1	n. s.
Leucine	−2 ± 1	−20 ± 35	−2 ± 5	−9 ± 6	0 ± 2	n.s.
Lysine	−4 ± 1*	−45 ± 20	−7 ± 6	−15 ± 6	−6 ± 1	P < 0.05

The subjects performed cycle exercise for 1 h with a reducedmuscle glycogen content in one leg. The values given are means ± S.E.M. for six subjects.

^*P < 0.05 indicates a difference from zero flux rates.