Table 3.

Comparison of Boltzmann parameters of fits to peak G–V and Q–V relationships for rSkM1 and hH1a Na⁺ channels after modification by site-3 toxins

Na+ channel isoform	Ionic or gating current relationship	V1/2 (mV)	Slope factor (mV)
rSkM1 (n= 6 cells)	G–V	−50 ± 3	−5.1 ± 0.3
	Q–V	−50 ± 6	−12.3 ± 1.7*
hH1a (n= 5 cells)	G–V	−61 ± 6	–5.8 ± 0.5
	Q–V	−62 ± 8	−11.5 ± 1.8*

^*Q–V values compared with G–V values for each isoform are significantly different at P < 0.05. V_1/2 is the half-point of the relationship (see eqns (1) and (2)).