Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ethanol at 2% does not alter single channel characteristics of control-incubated or FKBP12-stripped RyRs
| RyR | n | Po (ms) | To | Fo (s−1) |
|---|---|---|---|---|
| Control incubated (10−7 M Ca2+) | ||||
| Control | 3 | 0.100 ± 0.960 | 11.2 ± 10.4 | 6 ± 2 |
| Ethanol | 3 | 0.088 ± 0.086 | 4.6 ± 3.9 | 8 ± 6 |
| FKBP12 stripped (10−7 M Ca2+) | ||||
| Control | 5 | 0.297 ± 0.159 | 10.0 ± 5.0 | 25 ± 9 |
| Ethanol | 5 | 0.301 ± 0.151 | 11.0 ± 5.3 | 23 ± 8 |
Channel activity was measured over ~60 s periods before and after addition of ethanol. The data are given as means ± S.E.M.
