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. 1999 Feb 15;515(Pt 1):31–39. doi: 10.1111/j.1469-7793.1999.031ad.x

Figure 4. Effect of M2 mutations on channel open time.

Figure 4

Each bar indicates the weighted mean channel open time obtained from several recording sites for each of the constructs listed on the abscissa. The double exponential parameters used to compute the weighted mean open times are summarized in Fig. 5. Data were obtained at -100 mV. The weighted mean channel open times (±s.d.) and sample sizes presented above were as follows: ε(WT), 1.72 ± 0.44 ms (23); γ(N6S I7V), 1.65 ± 0.94 ms (12); γ(N6S), 1.97 ± 0.57 ms (12); ε(S6N), 2.94 ± 1.09 ms (14); ε(S6N V7I), 6.08 ± 1.99 ms (16); γ(WT), 4.91 ± 2.52 ms (20). The difference between the open times of ε(S6N V7I) and γ(WT) was not statistically significant (Student's two-tailed t test, P = 0.092).